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Ma X, Chen Z, Wang L, Wang G, Wang Z, Dong X, Wen B, Zhang Z (2018) The pathogenesis of diabetes mellitus by oxidative stress and inflammation: its inhibition by berberine
These effects were more noticeable in longer trials and when ALA was combined with dietary changes.29 A 2020 dose-response meta-analysis confirmed small but statistically significant reductions in weight and BMI across 18+ randomized controlled trials.30 However, waist circumference (WC) a marker of central obesity showed no consistent change, and the benefit appeared greater in women and with longer treatment durations
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Value: Excellent for those focused on quality and efficacy
Its greatest value may be as an adjunct to established cholesterol, glucose, inflammation, and kidney markers
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