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Laboratory protocols explore how senescent T cells, B cells, and other immune cells contribute to age-related immune dysfunction, while FOXO4-DRI administration provides researchers with methods for testing immune system restoration following senescent cell elimination

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[] This increase in mortality corresponds to an estimated loss of 7.5 million life-years, disproportionately impacting regions including Africa, Asia, and Latin America/Caribbean

To optimize clinical efficacy, a precise strategy, inhibition or activation, must be judiciously selected on the basis of the specific disease, its stage, and the role of LONP1