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17,18,19,20 Dysregulated lactylation contributes to the onset and progression of various cancers through metabolic adaptation, immune evasion, programmed cell death modulation, epigenetic rewiring, stemness maintenance, invasion, and metastasis

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Susceptibility to apoptosis of T lymphocytes from elderly humans is associated with increased in vivo expression of functional Fas receptors

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Both have decades of clinical use behind them, which provides a level of evidence that newer peptides like Dihexa and P21 have not yet achieved despite their promising preclinical results