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Semaglutide is available in an injectable form (subcutaneous injection) and as an oral drug (Rybelsus) in distinct doses

Always consult with your healthcare provider before making changes to your medication.

Compounded semaglutide can come in different formulations, as it is customized by a compounding pharmacy to meet the needs of an individual patient

Importantly, patients taking Rybelsus (oral semaglutide) should remember that this medication must be taken on an empty stomach with no more than 4 ounces of plain water, and they should wait at least 30 minutes before consuming any food, beverages, or other oral medicationsincluding alcohol

Quick answer Semaglutide is usually the clearest first GLP-1 choice for people who want a well-studied weekly medication, strong appetite control, and a familiar clinical evidence base