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the agency said in December that its Pharmacovigilance Risk Assessment Committee was seeking more information from the drugs makers, and that while at this point no conclusion can be drawn on a causal association, there are several issues that still need to be clarified. Late last week, a large review of electronic health records from the US found that GLP-1 drugs actually carried a lower risk of patients having suicidal thoughts compared with other medicines that work in different ways for diabetes and weight loss

(1, 2, 3) Another common claim is that about 24 percent of mitragynine (the main alkaloid in kratom) is converted to 7-OH in the human body

Results: nejm.org/doi/full/10.10 #ADA2023 Retatrutide, a TRIPLE agonist (GLP1, GIP, glucagon), just released phase 2 trial results demonstrating 25% weight loss in half of people with #obesity

Monthly costs typically fall in the range of 150 to 250