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Animal care and use All experiments involving animals were conducted in strict accordance with the recommendations in the Guidelines for Proper Conduct of Animal Experiments published by the Science Council of Japan and ethics approvals from the Kyushu University Institutional Review Board (approval No

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Supporting this hypothesis, a chronic unpredictable mild stress mouse model demonstrated that melatonin effectively restored aquaporin-4 polarization and rectified the compromised glymphatic system observed in this model [215]

[82] The name of the index is GAP and is based on gender [G], age [A], and two lung physiology variables [P] (FVC and DLCO) that are commonly measured in clinical practice to predict mortality in IPF

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