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Clin Endocrinol (Oxf) 2014;80(3):425-31

Studies using neuronal cell cultures have shown that IGF1 LR3 protects against many forms of cellular stress, including oxidant stress, excitotoxicity, and apoptotic stimuli

Human clinical trials in chronic venous ulcers have reported similar improvements, with GHK-Cu-treated ulcers demonstrating significantly increased granulation tissue formation and accelerated healing compared to placebo-treated controls

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