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SOD rapidly and specifically reduces superoxide radicals to hydrogen peroxide (H 2 O 2 ), while H 2 O 2 is decomposed to water by CAT and glutathione peroxidase (GPx) [28]

Redox Biol 69 , 103014 (2024)

We, among others, have demonstrated the antinociceptive and anti-inflammatory potential of nicorandil against different models of experimental pain 21,22,23,24,25

The CAPTAIN I and CAPTAIN II trials examined its effects on moderate to severe traumatic brain injury, defined as Glasgow Coma Scale scores between 7 and 12

Furthermore, the study showed that PCs curtail cell proliferation induced by glucose, insulin, and palmitate, although the precise mechanism remains unclear