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In some embodiments, the percentage of active agent is varied between about 1% and about 95%, between about 5% and about 80%, between about 10% and about 60% or more of the weight or volume of the total pharmaceutical formulation
Most evidence is from animal studies, but the consistency of results across 100+ studies and multiple tendon types is significant
Nevertheless, this made efgartigimod the first-in-class FcRn antagonist approved for clinical use, under the brand name VYVGART
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