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Temporal associationwhere acne develops shortly after starting B12 and improves after stoppingprovides the strongest clinical evidence for causation in individual cases
Professional imaging such as MRI or ultrasound can clarify the extent of tissue damage and guide appropriate treatment intensity
If given IV, it must be injected slowly (often over at least 5 minutes or diluted in a larger volume bag and infused)
It is noteworthy that initial urine osmolarity findings, despite not being immediate, indicated no significant differences between the groups
The use of IR in protein/polypeptide structure analysis has a long history, with the first spectra of proteins being reported as early as 1935 (Heintz, 1935
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