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doi: 10.3844/ajbbsp.2005.180.185

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In agreement with our studies, evidence from Yellons observations suggests that GLP-1 added before ischemia induced a significant reduction of infarct size as compared to the control group

Administering UA to adult rats either 24 h before middle cerebral artery occlusion (62.5 mg/kg, intraperitoneally) or 1 h after reperfusion (16 mg/kg, intravenously) can protect cultured hippocampal neurons from cell death induced by brain ischemia-related damage, including exposure to excitatory amino acids, glutamate, and the metabolic poison cyanide [139]

Hassan H, et al