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The finding that DM patients treated with GLP-1 RA and/or SGLT-2i showed a lower risk than those not treated with these drugs for each component of the primary endpoint supports a cardiac and renal protective effect of these drugs also during AMI hospitalization

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Although direct evidence for these interactions was not provided in the present study, our data point to mitochondrial oxidative stress and altered cellular energy sensing pathways as key questions to tackle in future investigations of SLC25A39 deficiency

Design and Characterization of MP0250, a Tri-Specific Anti-HGF/Anti-VEGF DARPin Drug Candidate