Systematic reviewGLP-1 class evidence2025 Efficacy of GLP-1 Receptor Agonists on Weight Loss, BMI, and Waist Circumference A broad meta-analysis anchor for GLP-1 weight-loss effect and class-level comparisons
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In the current study, the researchers demonstrated that semaglutide reduced binge-like alcohol drinking in both male and female mice, and that the effect was dose-dependent (i.e., greater amounts of semaglutide led to greater reductions in binge alcohol intake)
Xu W, Sun T, Wang J, Wang T, Wang S, Liu J, et al
CYP1A1/1A2-Ethoxyresorufin O-Deethylase (EROD), CYP2B1/2B2-Pentoxyresorufin O-Depentylase (PROD), and CYP3A4 - Benzyloxyresorufin O-Debenzylase (BROD) Assays The assays were performed as previously described [18, 19], with some modification