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Numerous factors influence its level, including kidney function, age, gender, diet, composition of the intestinal microbiota, and liver FMO activity

presence of free redox metals, Cu, Fe)

IGF-1 LR3 (Insulin-like Growth Factor 1 Long R3) is an 83-amino-acid synthetic variant of human IGF-1, engineered with two key structural modifications: a glutamic acid substitution for arginine at position 3 (R3) and a 13-amino-acid N-terminal extension peptide

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