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LAC donates acetyl groups to histones, regulating the expression of genes important for synaptic plasticity, including those genes that regulate levels of glutamatethe major excitatory neurotransmitter in the brain
In some embodiments, a composition or formulation disclosed herein has an ionic balance that is the same as or substantially the same as the endolymph
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MCS patients show increased plasma inflammatory cytokines such as interleukin-8 (IL-8), IL-10, interferon (IFN)-gamma, monocyte chemoattractant protein-1 (MCP-1), platelet derived growth factor BB (PDGF-BB), and vascular endothelial growth factor (VEGF) [23]
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