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Specifically, the hippocampal CA1 region of HFD fed animals showed noticeable damage, thinning of the pyramidal cell layers, disorderly and sparse cell arrangement, and clear signs of neuronal degeneration and necrosis

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GO analysis further showed that uridine supplementation restored biological processes in aged oocytes, including oxidative stress responses, iron ion homeostasis regulation, lipid metabolism, oxidative phosphorylation, cell cycle regulation, and DNA repair (Fig

TRT improves insulin sensitivity and lipid metabolism but does not directly clear hepatic fat