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An NNMT inhibitor like 5-amino-1MQ could help by stimulating the synthesis of NAD+, a vital cofactor in the electron transport chain

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Key areas of research interest include the following

The second is dose and route translation : even where an effect is real in a mouse, the human-equivalent dose is not a simple body-weight scaling, and as the route section above stressed there is no human bioavailability figure to anchor an oral-versus-injected comparison