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Effects of insulin-like growth factor I (IGF-I) therapy on body composition and insulin resistance in IGF-I gene deletion

Both preventative studies showing reducing UV-induced pigmentation and therapeutic trials demonstrating improvement in melasma and age-associated hyperpigmentation provide evidence for clinical relevance of topical antioxidants [55, 56, 66,67,68]

Kosek E, Cohen M, Baron R, Gebhart GF, Mico JA, Rice AS, et al

The success in restoring neuronal dynamics by optogenetic stimulation of key neuronal populations in AD models and reliability of TMS in human neurological disorders offers a suitable scenario where putative therapeutic tools could emerge