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The pharmacokinetics of semaglutide did not appear to be affected by hemodialysis, as the semaglutide exposure ratio of ESRD subjects to healthy subjects during dialysis (AUC 4896 ) was similar to the ratio obtained when subjects were not receiving dialysis (AUC 48 )

This is not medical advice

They also work by slowing down movement of food through the stomach and curbing appetite, thereby causing weight loss

That creates a genuine overdose risk with significantly amplified side effects

The authors of the secondary analysis also note that research can further focus on why semaglutide produced the effects they observed