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doi: 10.3390/molecules26040987 423 ZhouKRaffoulJJ

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P = 0.001) and an 8.5% reduction in mucopurulent sputum ( P = 0.041) ( ERS Clinical Practice Guidelines (2025): The European Respiratory Society updated its management guidelines, issuing a conditional recommendation for the use of mucoactive drugs like NAC in specific NCFB phenotypes, particularly those with high sputum production and frequent exacerbations ( 7.2 Consensus of the expert panel Ninety percent of experts came to a consensus that 600 mg of NAC, taken twice daily, may be beneficial for patients with NCF bronchiectasis, and emerging evidence on its role in reducing exacerbation supports the opinion of 70% experts that NAC improves lung functions in these patients

Lung damage is among the most severe repercussions of this condition