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During ischemia or periods of high energy demand, GLP-1RAs enhance ketone body utilization, providing additional energy for cardiomyocytes (92)

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In particular, tell your provider if you have or have a past history of: Type 1 or type 2 diabetes Thyroid cancer Pancreatitis Kidney disease Diabetic retinopathy Depression Suicidal thoughts or behavior Ileus Tell your provider if you are pregnant, planning to become pregnant, or breastfeeding

The STEP trials demonstrated an average body weight reduction of approximately 15% over 68 weeks in participants receiving 2.4 mg weekly, making it one of the most effective peptides for fat loss currently available