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doi: 10.1002/bab.1700 124 ShoenfeldY.ShererY.HaratsD

Every medication has side effects that can vary by individual, and GLP-1s are no exception

Conclusion The addition of glucagon receptor activation to GLP-1based pharmacotherapy appears paradoxical only when glucagon is considered in isolation

Safer, Clinically Approved Alternatives Available in the UK MHRA-licensed weight-management medicines including semaglutide (Wegovy), liraglutide (Saxenda), tirzepatide (Mounjaro), and orlistat offer established safety profiles and evidence-based alternatives to unlicensed peptide combinations

Gutniak MK, Linde B, Holst JJ, Efendic S