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Over time, persistent follicular inflammation contributes to progressive miniaturization and, in its most severe expression, irreversible fibrosis of the follicular unit

Cell viability was quantified using the Cell Counting Kit-8 (CCK8) assay

aureus produces alpha-toxin, a pore-forming toxin that inserts itself into the membranes of host cells, causing cell lysis and contributing to tissue destruction

In addition, some consumers who reported adverse reactions purchased the unapproved fat-dissolving drugs online and injected the drugs themselves