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GLP-1 receptors are also expressed in the colon, where activation may improve the gut microbiome and reduce inflammation

This reference does not suggest if a nootropic works or not -- but it does explain why it may be categorized as a nootropic, as well as serving as a starting point for additional research

In these athletes, LC is thought to promote the usage of fat in energy generation, preserving some of the muscles natural energy source, therefore delaying the point when they hit the wall. 16 17 Interestingly in a rat model, ALCAR and alpha-lipoic acid co-supplementation was able to improve metabolic function, burning energy more efficiently, whilst also reducing oxidative stress

Walfisch A, Al-maawali A, Moretti ME, et al

Different doses allow exploration of dose-dependent effects on metabolism, and long-term receptor activation supports reproducible outcomes