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La mayora de los pacientes comienzan a notar una reduccin de peso durante el primer mes de tratamiento , aunque los resultados ms significativos generalmente se observan despus de 12 a 16 semanas

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The main mechanism underlying this phenomenon is the loss of the suppressive activity of insulin to regulate lipolysis in a metabolic dysregulated visceral adipose tissue, even during times of nutrient excess [17]

Because of this, the recommended feeding rate for the pellets is higher200 grams per day for a 500 kg (1,100 lb) horse compared to 120 grams for the Premix

Fatigue: Some people report feeling more tired than usual