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Craniofacial Neuralgias Premise: The treatment of craniofacial neuralgias represents an area of dissatisfaction for specialists due to the complex understanding of the pathophysiology of neuropathic pain

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Supporting this, several studies have demonstrated upregulation of germ cell-specific genes and enhanced sperm parameters following PRP treatment [36, 64,65,66,67,68], further validating its potential to promote spermatogenesis

Patients who harbor mutated BRAF are given adjuvant anti-PD-1 therapy in combination with BRAF and MEK inhibitors, while patients with wild-type BRAF are given anti-PD-1, as opposed to anti-CTLA-4 due to toxicity (170)

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