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Patients with elevated baseline inflammatory markers (CRP, IL-6) or copper metabolism disorders may face higher risk of adverse reactions

For example, a phase IIb, double-blind, placebo-controlled study was conducted in adults with T2DM and MASH with fibrosis (F1-F3) on stable treatment with GLP-1 receptor agonists to receive efruxifermin 50 mg or placebo once weekly for 12 weeks

July 2026: Pharmacy Compounding Advisory Committee meets to formally review and process reclassification

Biochemical analysis The level of fasting blood glucose was measured by a glucose oxidase method-based assay kit (A154-1-1, Jiancheng Bioengineering Institute, Nanjing, China)

(PubMed) Lombard KA, Olson AL, Nelson SE, Rebouche CJ