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These limitations and mitigation strategies have been critically discussed in the section on glycolysis inhibition and were added to emphasize the translational challenges of 2-DG-based metabolic therapy

5f) and (ii) 69 genes that were differentially regulated at FDR C) that yields a functional variant of MOTS-c 67,68

When used appropriately, they can improve key aspects of sperm quality, including motility and DNA stability, and may increase the success rates of reproductive treatments using frozen-thawed sperm [33, 35]

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