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Isolation of active phytoconstituents mainly depends upon the solvent type, and the solvent selection depends on the plants heat tolerance, immiscibility with the aqueous phase, affinity for desired components, polarity value near the solute, and toxicity

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doi: 10.1186/s13045-022-01297-1 83 GuilhermeAHenriquesFBedardAHCzechMP