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Additionally, HUVEC were plated in 6-well plates (6 10 5 cells/well) for 24 h, and scratched

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Activation of the cAMP/PKA pathway induces loss of stress fibers (112), activation of regular arrangement of collecting venules (Rac) and Cell Division Cycle 42 (Cdc42) (113, 114), formation of filamentous pseudopods and lamellar pseudopods (114, 115) microfilament assembly (116), and inhibition of the Rho family of GTPases activity (117, 118), events which happen at the tip of migrating cells

Semin Cancer Biol 83:353376 Palliyaguru DL, Yuan JM, Kensler TW, Fahey JW (2018) Isothiocyanates: translating the power of plants to people