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Eric Topol of Scripps Research Translational Institute was more direct: "These peptides have no data to support their safety and efficacy." The clinical proponents argue that the FDA's safety concerns immunogenicity risk, impurity risk, organ toxicity are theoretically valid but speculative in practice
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Some define elevation as a value at or above 1,000 ng/L, which is the same as 1,000 pg/mL and roughly 738 pmol/L, while others set the bar at more than 1,000 pmol/L, closer to 1,355 pg/mL
Together these mechanisms map cleanly onto the demands of tendon, ligament, and muscle repair, and that is why it sits at the center of so many joint healing peptides conversations
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