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Therefore, considering significance of both NO-system and egr-1 gene-systems for inflammatory bowel disease (54) as well as for multiple sclerosis (55-57), these may be important also when confronted with severe complications of advanced and poorly controlled IBD as well as multiple sclerosis

Natural extracts and their bioactive compounds have recently gained recognition as potential lead molecules in drug discovery for cancer treatment (159,160)

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Evidence supports that redox and nutrient networks are intricately interlinked components of the plants adaptive machinery under abiotic stress