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Stay upright for at least 30 minutes after eating

Frequently Asked Questions How long do I need to hold GLP-1 drops under my tongue

In markets where there is state/PMI reimbursement of GLP-1 treatment for obesity (eg the US), retatrutide is likely to be reserved as a second-line GLP-1 for those who have failed to lose sufficient weight with a cheaper alternative (such as semaglutide or tirzepatide)

Recognizing the signs of stress and implementing relaxation techniques, such as yoga or meditation, can also be beneficial, as stress can significantly disrupt normal digestive function

However, the frequent and painful IM injections present a great burden for patients and their families, and subcutaneous (SQ) OHCbl administration has been suggested as an alternative parenteral route [9]