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Staying hydrated can mitigate side effects like nausea and constipation

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Once the GLP-1 receptor has been activated, semaglutide increases insulin production, lowers blood sugar levels, and slows gastric emptying

In metabolic conditions such as diabetes, prolonged hyperglycemia can damage small nerve fibers through multiple pathways including oxidative stress, accumulation of advanced glycation end products, and microvascular insufficiency affecting nerve blood supply