glp-1 and sarcopenia The Impact of Glucose-Lowering Drugs on in Type 2 Diabetes: Current Evidence Underlying Mechanisms Sarcopenia‐related changes in serum GLP‐1

Kussie, P

Mechanism of Action Ozempic's mechanism of action is centered around its ability to bind to GLP-1 receptors on pancreatic beta cells, which enhances insulin secretion only when glucose levels are elevated, thereby minimizing the risk of hypoglycemia

doi:10.1159/000098702

When blood sugar drops too low, dosage adjustments or medication reassessment may be required (24)

On the other hand GPx3 is negatively correlated with MAPK oncogenic signaling pathway (94), which suggests a potential antitumor effect in thyroid cancer, while a decrease in GPx3 levels predisposes to an increase in the size of primary tumors and the number of metastatic lymph nodes (95, 96)