Chronic use of NAD + boosters is not without risks, as previously shown for cardiovascular events in in a large retrospective epidemiological study 15,30
If additional glycemic control is needed, the dose can be increased to 1 mg once weekly after at least four weeks, and further to a maximum of 2 mg once weekly if necessary
References: Fedoreyeva, L
Of the eight donors who were on incretin therapy, seven had been taking sitagliptin, sold in pill form as Januvia and marketed by Merck, and one had been on exenatide, sold as Byetta by Bristol-Myers Squibb
In some embodiments, the amount of the compound(s) in each therapeutically useful formulation or composition is prepared in such a way that a suitable dosage will be obtained in any given unit dose of the compound