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Challenges in the field of senotherapy for AD, including target engagement and biomarker development, are addressed

The Wnt/-Catenin signaling pathway plays crucial roles in HFs development, including growth cycle restart and maintenance and HF cells proliferation and differentiation (Ito et al., 2007

Furthermore, GLP-1RAs have been shown to mitigate psoriasis severity by modulating the innate immune system, specifically through interactions with i NKT cells [208]

Nrf2 for cardiac protection: pharmacological options against oxidative stress

Abbreviations AAS: Antibiotic antimycotic solution -GST: Alpha-glutathione s-transferase ALT: Alanine aminotransferase ASGPR1: Asialoglycoprotein receptor 1 CD206: Mannose receptor CD32b: Fc fragment of IgG receptor IIb CYP3A4: Cytochrome P450 3A4 DILI: Drug-induced liver injury DMSO: Dimethyl sulfoxide IL: Interleukin KCs: Kupffer cells LDH: Lactate dehydrogenase LPS: Lipopolysaccharide LSECs: Liver sinusoidal endothelial cells LVX: Levofloxacin mBCI: Monochlorobimane MDMs: Monocyte-derived macrophages PBS: Phosphate buffered saline ROS: Reactive oxygen species RT: Room temperature TNF-: Tumor necrosis factor-alpha TVX: Trovafloxacin VPM: Vascular perfusion medium References Stevens, J