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Low Vitamin B12 and Lipid Metabolism: Evidence from Pre-Clinical and Clinical Studies

Deficiency in mitochondrial complex I can result in oxidative stress, heightening neuronal susceptibility to excitotoxic injury

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GLP-1R is present in the human choroid plexus, where GLP-1R analogs reduces cerebrospinal fluid secretion and intracranial pressure by increasing the intracellular concentration of cyclic adenosine monophosphate and inhibiting the Na + /K + ATPase pump in the choroid plexus [25]

Throughout this critical three-month recovery period, daily supplementation of B12 is essential