One randomized controlled trial (RCT) found that exenatide (2 mg weekly for 6 weeks), when combined with a nicotine replacement therapy patch, reduced nicotine cravings, withdrawal symptoms, and post-cessation weight gain, and increased nicotine abstinence compared to placebo or nicotine replacement therapy alone, in individuals who had smoked for at least a year and consumed 10 cigarettes daily [21]
May be preferable when consistent IGF-1 elevation is the goal
Studies show that patients on GLP-1 therapies experience modest increases in uric acid levels during the first months of treatment
That compared with a 2.1% weight loss, or less than 5 pounds, in patients who received a placebo
Retatrutide (also referred to by its development code LY3437943) is an investigational, once-weekly injection developed by Eli Lilly and Company