Research published in Ageing Research Reviews has explored the relationship between GHRH analogs, growth hormone secretion, and IGF-1 regulation, helping establish the physiological basis for their use in carefully selected patients (Merriam et al., 2003)
However, it is important to recognise that whilst they are widely available, the regulatory framework for food supplements differs significantly from that of licensed medicines, and claims made about their efficacy should be evaluated critically against available evidence
Today, peptides--the majority of which are imported from China in bulk and later analyzed by third party labs to obtain a certificate of analysis (COA)--are largely sold as as "research chemicals usually as a powder that requires mixing with sterile water for subcutaneous injection, or as a nasal spray, often accompanied by pseudo-medical dosing guides, social media testimonials, and before-and-after photos
These formulations should be applied to clean, dry skin either once or twice daily, depending on your skins tolerance and the product concentration
And in the latest survey posted by the International Foundation of Employee Benefit Plans in May, 55% of employers said they provide coverage of GLP-1s for diabetes only, while only 36% provide coverage for both diabetes and weight loss