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One of the mechanisms maybe the radiation-induced exosome export of miR-603 and the simultaneously up-regulation of IGF1 and IGF1R expression (Ramakrishnan et al., 2020)

The species studied included Sprague-Dawley rats, CD-1 mice, Beagle dogs, and cynomologus monkeys treated with-naphthoflavone or phenobarbital (all species), isoniazid (rat), pyrasole (monkey), dexamethasone (rat, mouse, monkey), rifampin (dog), or clofibric acid (rat, mouse, dog)

If you experience mild side effects like bloating or a slight headache, they typically resolve within a few days as your body adjusts to the supplement

Piccolo M, Ferraro MG, Iazzetti F, Santamaria R, Irace C

Mitochondria in the pathogenesis of systemic lupus erythematosus