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Carbamate pesticides, such as aldicarb, carbofuran, and ziram, are another class of chemical pesticides used on crops, that cause reversible carbamylation of AChE allowing accumulation of acetylcholine, and were related with neuronal damages, oxidative stress, increases the risk for dementia and Parkinson-like neuropathy (Trk Br et al., 2018)
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However, we believe that the notion of levels of evidence used to assess the efficacy of drugs cannot be applied in the same way to assess the safety of drugs
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