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The structural replacement of a ketone with an ester makes it possible for loteprednol to be metabolized by esterasesthus limiting the potential side effects of this medication

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Theoretical or documented interactions include: Immunosuppressants (particularly ciclosporin, where clinical interaction has been documented) Medications metabolised by CYP3A4 or CYP2D6 enzymes Medications that are P-glycoprotein substrates Consult your pharmacist or GP before taking berberine alongside any regular medications, particularly those with a narrow therapeutic window

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