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The therapeutic efficacies of this IC were similar to those of interferon- treatment and the protocol for treatment was deemed to merit further optimization 83 Importantly, transient flares of alanine aminotransferase (ALT), reflecting injuries in liver function, were observed in a small percentages of IC-treated patients, but liver functions became normal during treatment or at the follow-up period

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10.1021/bi00010a023 Margalit A, Hauser SD, Zweifel BS, Anderson MA, Isakson PC: Regulation of prostaglandin biosynthesis in vivo by glutathione