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Current guidelines recommend discontinuing semaglutide and tirzepatide at least 2 months before attempting pregnancy due to their long half-lives and prolonged effects in the body
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Semaglutide has demonstrated cardiovascular benefits in clinical trials (SELECT trial), reducing the risk of major adverse cardiovascular events, though this is not currently part of Wegovy's licensed indication in the UK
Understanding the broader landscape of peptide safety considerations provides context for recognizing warning signs across all peptide types
Understanding semaglutide onset timing helps set appropriate expectations during the early transition phase
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