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Keywords Alzheimer's disease, GHK-Cu, 5xFAD transgenic mouse, intranasal administration, amyloid plaques, neuroinflammation Introduction Alzheimer's disease (AD) is a complex disease that was the seventh leading cause of mortality in the US in 2022 [1]

Separate studies demonstrated anti-anxiety effects in rats at remarkably low doses (0.5 mg/kg), with effects appearing within 12 minutes and including increased exploration of open and lighted spaces, a standard measure of reduced anxiety in rodent models

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Because it inhibits bacterial growth, it's safer to use over time than regular sterile water