A new tool in treatment In 2021, the FDA approved the GLP-1 receptor agonist, semaglutide, known most commonly as Wegovy, as an aid in weight management
Standard coagulation tests like PT, APTT, and INR remained unchanged, suggesting the anti-clotting effect works through platelet function rather than the coagulation cascade
In addition, intranasal administration offers the potential advantages of a more rapid onset of action and avoidance of first-pass metabolism [28]
Outcome according to KRAS-, NRAS- and BRAF-mutation as well as KRAS mutation variants: pooled analysis of five randomized trials in metastatic colorectal cancer by the AIO colorectal cancer study group
That means we need to be a little more thoughtful about our approach with initiating and titrating these medications in patients with poorly controlled diabetes