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Together, these changes help improve overall metabolic health in a big way

Both these intact forms as well as inactivated GLP-1 metabolites are also rapidly cleared from the circulation via the kidneys

Adults also can qualify if they have a BMI of 27 or greater, which puts them in the category of being overweight, if they also have at least one weight-related condition such as diabetes, hypertension or high cholesterol

Initially approved for diabetes treatment, semaglutide gained recognition for its side effect of weight loss