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For instance, these cells identify melanocytes via Major Histocompatibility Complex (MHC) class I molecules and induce apoptosis through the directed release of perforin and granzyme B, while IFN- secretion exacerbates local inflammation and amplifies the autoimmune response, constituting a key pathological event in vitiligo (5)

Enhanced protein glutathiolation and oxidative stress in cigarette smokers

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14 Functional neuroimaging studies suggest compensatory responses, such as upregulation of dopamine synthesis and downregulation of synaptic dopamine reuptake, occur as adaptive mechanisms beginning in the premotor stage of PD

showed that p53 directly activated CPT1C transcription, conferring to tumor cells resistance 46