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USA 102 , 90569061 (2005)

We have previously investigated the acute effects of lixisenatide injection compared to saline in measurements of functional magnetic resonance imaging (fMRI) responses to visual food cues

Nrf2-MafG heterodimers contribute globally to antioxidant and metabolic networks

Dopaminergic pathways are similarly affected, with reduced tyrosine hydroxylase activity leading to diminished dopamine in the basal ganglia and prefrontal cortex, manifesting as anhedonia, reduced motivation, and psychomotor retardation (73, 74)